Muh Muh Muh My Corona (virus)

Exactly. Assumes facts not in evidence.
This is also a guy who says we could avoid lockdowns and beat this thing if everybody had copious amounts of in-home, rapid-results testing. Vaccines wouldn't be as vital. And that may be true. But this is like saying I'd be better off financially if I won the lottery.

 

Now I think you are just playing with me.

 

No. It is not. Every single doctor who prescribes an antibiotic expects the patient to take the dosage prescribed at the time interval specified until the Rx runs out. Period.

Taking half an ABX Rx leads to resistant infections.

It's a horrible idea.

 

It'll be interesting to see if the reduced dose DeSantis is suggesting has arisen out of Pfizer "production issues" - as he's claiming in this morning's news conference - or because the My Pillow guy didn't order enough when he had the chance.

 

Here's the figure in the New England Journal of Medicine paper that those folks are getting hopped up about ...



It can be kinda hard to get your mind around what's being argued (even though the arithmetic is not difficult). They only have data for a single-dose regimen that extends from the administering of the first dose to the administering of the second dose (21 days, I think). And over that period, the vaccine demonstrated 52% effectiveness.

But that absolutely does not mean a one-dose regimen would be 52% effective. We simply don't know how effective a one-dose regimen would be, because we'd need to compare a one-dose regimen to a placebo over a much longer period than 21 days. Maybe, ultimately, a one-dose regimen might be waaaay less effective over the long haul. On the other hand, it might be only marginally less effective (say, 85% as opposed to 95%). So too in the comparison of a one-dose regimen to a two-dose regimen.

That immunologist/epidemiologist's "80%" is a "what-if?" that's somewhat in line with a ballpark projection of the difference in COVID incidence beyond 21 days. So you'd compare the single-dose regimen's incidence of 39/4.015 to the placebo's incidence of 275/3.982 to come up with about 86% effectiveness.

The idea that a one-dose regimen might, as a matter of public policy, be preferable to a two-dose regimen is not some out-there thing. The vaccine is and will remain scarce (so too the infrastructure required to get it "out there"). So people are going to get sick and die either way. But it is entirely within the realm of possibility that a less-effective vaccine that is distributed twice as widely will result in less illness/death than the more-effective one.

 

Really fucking hope we get more than 90 minutes to digest this post ...

 

Solid Steel can’t seem to use Google for shit.

 

The idea that an elected official would give credence to the "you can get away with taking it just once" crowd at this stage in the process makes me think that person wants to sabotage his citicenry's health.

 

Because there will always be believers.

 

I am sorry, friends, but I think what Gov. DeSantis said is commendable. One dose is partly effective and will at least begin to “stem” COVID 19. He makes no suggestion that Dose 2 is not important, as well.

I commend him.

 

If you don't put it in quote marks the system autocorrects it to "pussycat" ...