I think the G5 leagues could survive quite well playing exclusively on Saturday, maybe an occasional Friday night game. Every game can be streamed, so finding a linear broadcast window isn't as important. College football as it once was.
I absolutely LOVE the kickoff times for OSU games this season, now that they are not locked into being jammed into an ESPN/FOX/Pac-12 box. Saturday home games are great for the local economy. They're great for spectators, most of whom live within a 3-4-hour drive. Campus is alive, downtown is packed on Friday nights.
I know the MAC loves MACtion, but IMHO it just kills the fan base and the local communities to play on a Tuesday or Wednesday night as opposed to Saturdays.